![]() The ppl_prep_data function examines the presence and class of specific columns (e.g., LEFT_PUPIL_SIZE, RIGHT_PUPIL_SIZE, LEFT_IN_BLINK, RIGHT_IN_BLINK, TIMESTAMP, and TRIAL_INDEX) to ensure they are present in the data and appropriately assigned (e.g., categorical variables are encoded as factors). In order for the functions in the package to work appropriately, the data must be in a specific format, i.e., SR sample report. For more information about dplyr, please refer to its reference manual and extensive collection of vignettes. Lastly, the functions included here, internally make use of dplyr for manipulating and restructuring data. Additionally, it is preferable to export to a. The presence of necessary columns will also be checked internally when processing the data. This will ensure that you have all of the necessary columns for the functions contained in this package to work. The Sample Report should be exported along with all available columns. If you have not aligned your data to a particular message in Data Viewer, please refer to the Message Alignment vignette for functions related to this. However, this package is also able to preprocess data without a specified relative interest period. For this basic example, it is assumed that you have specified an interest period relative to the onset of the critical stimulus in Data Viewer (i.e., aligned to a specific sample message). Second, your data must have been exported using SR Research Data Viewer software, i.e., a sample report. Here, the clinical manifestations, pathogenesis, relationship between Adie's pupil and diseases, and differential diagnosis of Adie's pupil are reviewed.Before using this package a number of steps are required: First, your pupil size data must have been collected using an SR Research Eyelink eye tracker. ![]() Differential diagnosis between Adie's pupil, oculomotor nerve palsy, anticholinergic drug overdose, Argyll-Robertson pupil, and congenital mydriasis need to be identified by the physician. It is essential for clinicians to improve their understanding of the disease to avoid misdiagnosis. Pilocarpine can be used to treat ophthalmologic symptoms, such as blurred vision, for which patients might visit an ophthalmologist or neurologist. The ophthalmological symptoms and pupil abnormalities can disappear after active treatment of the primary disease. ![]() Through a literature review, we found that Adie's pupil is mainly associated with infectious diseases, most commonly syphilis, followed by immune diseases and paraneoplastic syndromes. The pathogeneses of Adie's pupil are complex, some of which are insidious and lack corresponding specific diseases. The pupil on the affected side is sensitive to low concentrations of pilocarpine. The direct and indirect light reflection from the pupil on the affected side disappears. The pupil of the affected side is significantly larger than that on the healthy side. Most patients have unilateral eye involvement. Adie's pupil, also called tonic pupil, is mainly seen in young women. ![]()
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